Particularly Hazardous Substances

Particularly Hazardous Substances

Duke OESO is no longer maintaining a list of particularly hazardous substances. We now provide the GHS Lookup Tool as well as other resources to help labs identify chemical hazards so the appropriate steps can be taken to provide a safe working environment.

If you have chemicals that do not appear in the GHS Lookup Tool, review the GHS Criteria for particularly hazardous and high risk chemicals and the SDSs for your chemicals to determine if they are particularly hazardous and/or high risk. To request that chemicals be added to future versions of the GHS Lookup Tool, email OESO at labsafety@dm.duke.edu with the CAS number and name of the chemical and a copy of or link to your supplier’s SDS.

Any particularly hazardous or high risk chemicals identified must be included on your lab’s list of particularly hazardous substances (part of your lab-specific chemical hygiene plan) and your lab must create and implement customized standard operating procedures for these materials. (Labs may use the OESO SOP Template or integrate the safety procedures into the experimental protocol.) For high-risk materials, OESO approval is required for highly toxic materials and PI approval is required for physical hazards. Departmental approval may also be required.